Gene Expression Biochemistry and Molecular Biology Biology
Gene Expression Biochemistry and Molecular Biology Biology
Includes sites related to processes of the Central Dogma of Genetics: transcriotion to mRNA, mRNA splicing, translation to polypeptides, modification of the resulting polypeptides by specific proteolysis and conjugation to carbohydrates, lipids and prosthetic groups. Also includes control of the processes: pre-transcriptional by factors controlling transcription to mRNA and post-transcriptional control by RNA interference (iRNA). A separate sub-category includes sites related to viral reverse transcription.
Top: Science: Biology: Biochemistry and Molecular Biology: Gene Expression
See Also:
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Epigenetics Research - News, jobs, recent literature, lab registry and an ontologically driven database that is updated daily.
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Eukaryotic Gene Expression Problem Set - Multiple choice questions about post-transcriptional modification of RNA, promoters, and nuclear RNA processing. From: University of Arizona, USA 1997.
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Genome-Wide Expression - Report on a project to analyze the transcriptional regulatory circuitry of the yeast cell. From the Young Lab at the Whitehead Institute for Biomedical Research.
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Serial Analysis of Gene Expression - Explanation of SAGE, a method for analysis of gene expression patterns.
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Laboratory of Intelligent Systems - Project at the Ecole Polytechnique Fédérale de Lausanne (EPFL) creating electronic models of the evolution of gene expression, neural development and similar evolution processes.
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Wikipedia: RNA Splicing - Article on the process and pathways catalyzed by the spliceosome, in the cell nucleus of eukaryotic cells prior to translation.
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Wikipedia: Gene Expression - Article with overview, and linking to definitions of topics of current interest to the public.
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RiboWeb Project - Knowledge base that combines data on the structure of the prokaryotic 30S ribosomal subunit that initiates the translation of mRNA into protein, its function and related links and references.
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Taq DNA Polymerase - Product presentation from ShineGene Molecular Biotec Inc, Shanghai.
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Biochemistry of Nucleic Acids - Lecture notes on nucleic acid structure, DNA replication and repair, the genetic code and translation, as well as cancer genes, from Oregon State University, USA 2003.
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Wikipedia: Operon - Article on the group of genes in primitive organisms that are controlled by one operator and one promoter to be activated together.
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Wikipedia: Signal Peptide - Article on the short sequences that direct the post-translational transport of proteins after synthesis.
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Gene Expression: Transcription - Resource for transcription events during gene formation including schematic diagrams.
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Alternative Splicing - Resource for intervention in the key steps in post-translocation regulatory process, with analysis tools and implications in pathologies. Maintained by Exonhit Therapeutics SA, Paris, France.
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Wikipedia: Shine-Dalgarno Sequence - Article on signals that initiate protein synthesis in bacteria.
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Computer simulation of molecular biology experiments - Computer simulation of PCR amplification, AFLP-PCR and restriction digest of complete bacterial genomes.
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Control of Gene Expression - A collection of diagrams illustrating the fundamentals of molecular biology.
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Regulation of Gene Expression - Overview of different aspects of gene expression, including transcription, chromatin modification, and analysis of whole genomes, from Massachusetts Institute of Technology, Cambridge, Mass, USA.
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Wikipedia: Promoter - Article on the sequence located upstream of a gene that enables its translation.
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Genomes to Life - The US Department of Energy at Oak Ridge program for research in moleular biology: goals and results.
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Wikipedia: Genetic Code - Article on the relationship between the nucleic acid base sequence and the corresponding polypeptide amino acid sequence.
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European Sequencing of Tobacco - A collaboration between Advanced Technologies (Cambridge) Ltd and Tobacco Institute of Bergerac to sequence a large number of tobacco genes.
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Role of the Ribosome - Illustrated explanation of the ribosomal protein synthesis by Gwen V. Childs, University of Texas, Galveston, TX.
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Wikipedia: Expressed Sequence Tag - Article explaining EST; short sub-sequences of genes, used in mRNA sequencing and in construction of DNA microarrays.
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Genlantis - Reagents for transfection, gene expression, gene silencing, RNA interference, primary cell culture and sample preparation in proteomics research.
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JCat - Bioinformatic Tool to adapt Codon Usage to sequenced prokaryotes and eukaryotes, from the Technical University of Braunschweig, Germany.
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Gene Expression - Independent forum for discussion of gene expression.
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6th International Summer School "Biocomplexity from System to Gene" - Summaries and reports from a summer school in Istambul, Turkey.
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Anatomy of a Comparative Gene Expression Study - Clear explanation of the process of comparing the gene expression in two cell populations or tissue samples by fluorescent microarray technique.
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Reportergene - Information and news related to reporter genes, that are used to monitor activation of genes and groups of genes. The community reviews trends in reporter genes development from peer-reviewed research.
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