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Fifth Disease Conditions and Diseases HealthFifth disease is a viral illness caused by the human parvovirus B19. It produces a distinctive red rash on the face, body, arms, and legs. Because it is caused by a virus, antibiotics don't help. For most people, the symptoms are not bad enough to need medicine. Once someone has had fifth disease, they are immune and can't get it again. Top: Kids and Teens: Health: Conditions and Diseases: Fifth Disease See Also:
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